Description
Product Characteristics:
Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Subcellular location: Cytoplasm
Synonyms: KIAA0900, Protein WAVE-3, Protein WAVE3, SCAR3, Verprolin homology domain containing protein 3, Verprolin homology domain-containing protein 3, WASF3, WASF3_HUMAN, WASP family protein member 3, WAVE3, Wiskott Aldrich syndrome protein family member 3, Wiskott-Aldrich syndrome protein family member 3.
Target Information: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. [provided by RefSeq, Jul 2008]